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Proliferation of preneoplastic lesions after discontinuation of chronic DEN feeding in the development of hepatomas in rat.

Diethylnitrosamine (DEN, 10 mg/kg/day) was fed to rats for 2, 4 and 6 weeks. At different times after feeding with DEN was stopped, growth of preneoplastic lesions has been correlated with pathological evolution (preneoplastic foci, neoplastic nodules and hepatomas). The proliferating fraction in th...

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Detalles Bibliográficos
Autores principales: Barbason, H., Betz, E. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1981
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010815/
https://www.ncbi.nlm.nih.gov/pubmed/7295512