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Proliferation of preneoplastic lesions after discontinuation of chronic DEN feeding in the development of hepatomas in rat.
Diethylnitrosamine (DEN, 10 mg/kg/day) was fed to rats for 2, 4 and 6 weeks. At different times after feeding with DEN was stopped, growth of preneoplastic lesions has been correlated with pathological evolution (preneoplastic foci, neoplastic nodules and hepatomas). The proliferating fraction in th...
Autores principales: | Barbason, H., Betz, E. H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1981
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010815/ https://www.ncbi.nlm.nih.gov/pubmed/7295512 |
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