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Cimetidine enhancement of cyclophosphamide antitumour activity.

Male DBA2 mice were given 10(6) P-388 leukaemic cells i.p. and cimetidine (CMT) at 100 mg/kg 1 day for 10 days, or as a single 100 mg/kg injection 30 min before cyclophosphamide (CTX). CMT significantly prolonged the survival of groups of mice receiving 50, 100 and 200 mg/kg of CTX 3 days after tumo...

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Detalles Bibliográficos
Autores principales: Dorr, R. T., Alberts, D. S.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1982
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010952/
https://www.ncbi.nlm.nih.gov/pubmed/7059463