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Clonal variation in the sensitivity of B16 melanoma to m-AMSA.

A hypothesis that m-AMSA may have greater cytotoxicity in melanin-containing tumour tissues, because it may reversibly bind to melanin, leading to prolonged drug exposure, was examined. Clonal lines of B16 melanoma which differed widely in pigmentation level were selected by isolating artificial lun...

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Detalles Bibliográficos
Autores principales: Stephens, T. C., Peacock, J. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1982
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011041/
https://www.ncbi.nlm.nih.gov/pubmed/6896455