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Structure/activity relationships for the enhancement by electron-affinic drugs of the anti-tumour effect of CCNU.

Using a regrowth-delay assay, we investigated structure/activity relationships for the enhancement by electron-affinic agents of the anti-tumour effect of the nitrosourea CCNU against the KHT sarcoma in C3H mice. A series of neutral 2-nitroimidazoles similar in electron affinity but varying in octan...

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Detalles Bibliográficos
Autores principales: Workman, P., Twentyman, P. R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1982
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011106/
https://www.ncbi.nlm.nih.gov/pubmed/7150475