Hypoxic cell sensitization to radiation damage by a new radiosensitizer: cis-dichloro-bis(1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole-N3)platinum(II) (flap).

A new, stable platinum coordination complex (FLAP) containing the 5-nitroimidazole, metronidazole, has been prepared and characterized. The square-planar platinum(II) complex has two metronidazole molecules and two chlorine atoms in the cis configuration. The properties of FLAP differ significantly...

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Detalles Bibliográficos
Autores principales: Bales, J. R., Sadler, P. J., Coulson, C. J., Laverick, M., Nias, A. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1982
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011175/
https://www.ncbi.nlm.nih.gov/pubmed/6890846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011175/
https://www.ncbi.nlm.nih.gov/pubmed/6890846

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