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Modification by WR 2721 of the response to chemotherapy of tumours and normal tissues in the mouse.

The sulphydryl compound WR 2721 has been combined with a range of cytotoxic drugs in the mouse and the effects upon tumours and normal tissues determined. In the acute lethality (LD50/30) assay, mean protection factors produced by WR 2721 (200 or 400 mg kg-1) were generally less than 1.3 for cycloph...

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Detalles Bibliográficos
Autor principal: Twentyman, P. R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1983
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011245/
https://www.ncbi.nlm.nih.gov/pubmed/6295428