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An investigation of the possibility of chemosensitization by clinically achievable concentrations of misonidazole.

Experiments have been carried out both in vitro and in vivo to examine the possibility of chemosensitization by misonidazole (MISO) at concentrations which are achievable in the clinic. Using multicellular tumour spheroids in vitro we found that a 16 h pre-incubation with 100 micrograms ml-1 MISO un...

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Detalles Bibliográficos
Autores principales: Twentyman, P. R., Workman, P.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1983
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011280/
https://www.ncbi.nlm.nih.gov/pubmed/6824566