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The mode of action of cis dichloro-bis (isopropylamine) trans dihydroxy platinum IV (CHIP) studied by the analysis of chromosome aberration production.

The induction of chromosome damage by the Platinum complex CHIP in Chinese hamster ovary (CHO) cells has been studied, together with the relationship between cell survival and aberration frequency. The type and frequency of chromosome aberrations observed in asynchronous and G1 phase treated cells i...

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Detalles Bibliográficos
Autores principales: Bocian, E., Laverick, M., Nias, A. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1983
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011329/
https://www.ncbi.nlm.nih.gov/pubmed/6849795