Ankyrin-B Syndrome: Enhanced Cardiac Function Balanced by Risk of Cardiac Death and Premature Senescence

Here we report the unexpected finding that specific human ANK2 variants represent a new example of balanced human variants. The prevalence of certain ANK2 (encodes ankyrin-B) variants range from 2 percent of European individuals to 8 percent in individuals from West Africa. Ankyrin-B variants associ...

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Detalles Bibliográficos
Autores principales: Mohler, Peter J., Healy, Jane A., Xue, Hui, Puca, Annibale A., Kline, Crystal F., Rand Allingham, R., Kranias, Evangelia G., Rockman, Howard A., Bennett, Vann
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2013943/
https://www.ncbi.nlm.nih.gov/pubmed/17940615
http://dx.doi.org/10.1371/journal.pone.0001051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2013943/
https://www.ncbi.nlm.nih.gov/pubmed/17940615
http://dx.doi.org/10.1371/journal.pone.0001051

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