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Malaria Impairs T Cell Clustering and Immune Priming despite Normal Signal 1 from Dendritic Cells

Interactions between antigen-presenting dendritic cells (DCs) and T cells are essential for the induction of an immune response. However, during malaria infection, DC function is compromised and immune responses against parasite and heterologous antigens are reduced. Here, we demonstrate that malari...

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Detalles Bibliográficos
Autores principales: Millington, Owain R, Gibson, Vivienne B, Rush, Catherine M, Zinselmeyer, Bernd H, Phillips, R. Stephen, Garside, Paul, Brewer, James M
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014797/
https://www.ncbi.nlm.nih.gov/pubmed/17937497
http://dx.doi.org/10.1371/journal.ppat.0030143