Muscleblind-like 1 interacts with RNA hairpins in splicing target and pathogenic RNAs

The MBNL and CELF proteins act antagonistically to control the alternative splicing of specific exons during mammalian postnatal development. This process is dysregulated in myotonic dystrophy because MBNL proteins are sequestered by (CUG)(n) and (CCUG)(n) RNAs expressed from mutant DMPK and ZNF9 ge...

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Detalles Bibliográficos
Autores principales: Yuan, Yuan, Compton, Sarah A., Sobczak, Krzysztof, Stenberg, Myrna G., Thornton, Charles A., Griffith, Jack D., Swanson, Maurice S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018611/
https://www.ncbi.nlm.nih.gov/pubmed/17702765
http://dx.doi.org/10.1093/nar/gkm601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018611/
https://www.ncbi.nlm.nih.gov/pubmed/17702765
http://dx.doi.org/10.1093/nar/gkm601

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