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Cdc18/CDC6 activates the Rad3-dependent checkpoint in the fission yeast

A screen for genes that can ectopically activate a Rad3-dependent checkpoint block over mitosis in fission yeast has identified the DNA replication initiation factor cdc18 (known as CDC6 in other organisms). Either a stabilized form of Cdc18, the Cdc18-T6A phosphorylation mutant, or overexpression o...

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Detalles Bibliográficos
Autores principales: Fersht, Naomi, Hermand, Damien, Hayles, Jacqueline, Nurse, Paul
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018612/
https://www.ncbi.nlm.nih.gov/pubmed/17690116
http://dx.doi.org/10.1093/nar/gkm527