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A facilitated tracking and transcription mechanism of long-range enhancer function

In the human ε−globin gene locus, the HS2 enhancer in the Locus Control Region regulates transcription of the embryonic ε-globin gene located over 10 kb away. The mechanism of long-range HS2 enhancer function was not fully established. Here we show that the HS2 enhancer complex containing the enhanc...

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Detalles Bibliográficos
Autores principales: Zhu, Xingguo, Ling, Jianhua, Zhang, Ling, Pi, Wenhu, Wu, Min, Tuan, Dorothy
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018613/
https://www.ncbi.nlm.nih.gov/pubmed/17704132
http://dx.doi.org/10.1093/nar/gkm595