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Ligand-induced folding of the thiM TPP riboswitch investigated by a structure-based fluorescence spectroscopic approach

Riboswitches are genetic control elements within non-coding regions of mRNA. They consist of a metabolite-sensitive aptamer and an adjoining expression platform. Here, we describe ligand-induced folding of a thiamine pyrophosphate (TPP) responsive riboswitch from Escherichia coli thiM mRNA, using ch...

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Detalles Bibliográficos
Autores principales: Lang, Kathrin, Rieder, Renate, Micura, Ronald
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018614/
https://www.ncbi.nlm.nih.gov/pubmed/17693433
http://dx.doi.org/10.1093/nar/gkm580