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β-Catenin binds to the downstream region and regulates the expression C-reactive protein gene

C-Reactive protein (CRP) is a major acute-phase response protein, which is activated by various cytokines. We investigated the mechanism of TNF-α-induced CRP expression and found that the p50 subunit of NF-κB was responsible for the transcriptional activation of CRP. Since the p50 protein acts as a...

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Detalles Bibliográficos
Autores principales: Choi, Yong Seok, Hur, Jung, Jeong, Sunjoo
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018623/
https://www.ncbi.nlm.nih.gov/pubmed/17704137
http://dx.doi.org/10.1093/nar/gkm547