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Biochemical reconstitution of abasic DNA lesion replication in Xenopus extracts

Cellular DNA is under constant attack from numerous exogenous and endogenous agents. The resulting DNA lesions, if not repaired timely, could stall DNA replication, leading to genome instability. To better understand the mechanism of DNA lesion replication at the biochemical level, we have attempted...

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Detalles Bibliográficos
Autores principales: Liao, Shuren, Matsumoto, Yoshihiro, Yan, Hong
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018634/
https://www.ncbi.nlm.nih.gov/pubmed/17702761
http://dx.doi.org/10.1093/nar/gkm552