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Filtering genes to improve sensitivity in oligonucleotide microarray data analysis

Many recent microarrays hold an enormous number of probe sets, thus raising many practical and theoretical problems in controlling the false discovery rate (FDR). Biologically, it is likely that most probe sets are associated with un-expressed genes, so the measured values are simply noise due to no...

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Detalles Bibliográficos
Autores principales: Calza, Stefano, Raffelsberger, Wolfgang, Ploner, Alexander, Sahel, Jose, Leveillard, Thierry, Pawitan, Yudi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018638/
https://www.ncbi.nlm.nih.gov/pubmed/17702762
http://dx.doi.org/10.1093/nar/gkm537