Cargando…

DNA polymerase proofreading: active site switching catalyzed by the bacteriophage T4 DNA polymerase

DNA polymerases achieve high-fidelity DNA replication in part by checking the accuracy of each nucleotide that is incorporated and, if a mistake is made, the incorrect nucleotide is removed before further primer extension takes place. In order to proofread, the primer-end must be separated from the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fidalgo da Silva, Elizabeth, Reha-Krantz, Linda J.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2007
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018640/ https://www.ncbi.nlm.nih.gov/pubmed/17702757 http://dx.doi.org/10.1093/nar/gkm591

Ejemplares similares

Proofreading exonuclease activity of human DNA polymerase δ and its effects on lesion-bypass DNA synthesis
por: Fazlieva, Ruzaliya, et al.
Publicado: (2009)

The 3′–5′ proofreading exonuclease of archaeal family-B DNA polymerase hinders the copying of template strand deaminated bases
por: Russell, Henry J., et al.
Publicado: (2009)

Mechanistic consequences of temperature on DNA polymerization catalyzed by a Y-family DNA polymerase
por: Fiala, Kevin A., et al.
Publicado: (2008)

Duplex strand joining reactions catalyzed by vaccinia virus DNA polymerase
por: Hamilton, Michael D., et al.
Publicado: (2007)

Plant organellar DNA polymerases are replicative and translesion DNA synthesis polymerases
por: Baruch-Torres, Noe, et al.
Publicado: (2017)

Lineage-specific variations in the trigger loop modulate RNA proofreading by bacterial RNA polymerases
por: Esyunina, Daria, et al.
Publicado: (2016)

Polymerase-catalyzed synthesis of DNA from phosphoramidate conjugates of deoxynucleotides and amino acids
por: Adelfinskaya, O., et al.
Publicado: (2007)

Mechanism of double-base lesion bypass catalyzed by a Y-family DNA polymerase
por: Brown, Jessica A., et al.
Publicado: (2008)

The DNA polymerase III holoenzyme contains γ and is not a trimeric polymerase
por: Dohrmann, Paul R., et al.
Publicado: (2016)

A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis
por: Juárez, Raquel, et al.
Publicado: (2006)

Promiscuous DNA synthesis by human DNA polymerase θ
por: Hogg, Matthew, et al.
Publicado: (2012)

Cooperative motion of a key positively charged residue and metal ions for DNA replication catalyzed by human DNA Polymerase-η
por: Genna, Vito, et al.
Publicado: (2016)

Noncanonical prokaryotic X family DNA polymerases lack polymerase activity and act as exonucleases
por: Prostova, Maria, et al.
Publicado: (2022)

Topoisomerase II minimizes DNA entanglements by proofreading DNA topology after DNA strand passage
por: Martínez-García, Belén, et al.
Publicado: (2014)

Low-fidelity DNA synthesis by human DNA polymerase theta
por: Arana, Mercedes E., et al.
Publicado: (2008)

Quantitative analysis of the efficiency and mutagenic spectra of abasic lesion bypass catalyzed by human Y-family DNA polymerases
por: Sherrer, Shanen M., et al.
Publicado: (2011)

Expanding the repertoire of DNA polymerase substrates: template-instructed incorporation of non-nucleoside triphosphate analogues by DNA polymerases β and λ
por: Crespan, Emmanuele, et al.
Publicado: (2007)

Calcium-driven DNA synthesis by a high-fidelity DNA polymerase
por: Ralec, Céline, et al.
Publicado: (2017)

A trimeric DNA polymerase complex increases the native replication processivity
por: Mikheikin, Andrey L., et al.
Publicado: (2009)

Significant contribution of the 3′→5′ exonuclease activity to the high fidelity of nucleotide incorporation catalyzed by human DNA polymerase ϵ
por: Zahurancik, Walter J., et al.
Publicado: (2014)

Mechanism of strand displacement synthesis by DNA replicative polymerases
por: Manosas, Maria, et al.
Publicado: (2012)

The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins
por: Zhong, Xuejun, et al.
Publicado: (2006)

An archaeal family-B DNA polymerase variant able to replicate past DNA damage: occurrence of replicative and translesion synthesis polymerases within the B family
por: Jozwiakowski, Stanislaw K., et al.
Publicado: (2014)

Regulation of B family DNA polymerase fidelity by a conserved active site residue: characterization of M644W, M644L and M644F mutants of yeast DNA polymerase ε
por: Pursell, Zachary F., et al.
Publicado: (2007)

A non-canonical multisubunit RNA polymerase encoded by a giant bacteriophage
por: Yakunina, Maria, et al.
Publicado: (2015)

Novel inhibition of archaeal family-D DNA polymerase by uracil
por: Richardson, Tomas T., et al.
Publicado: (2013)

Carcinogenic adducts induce distinct DNA polymerase binding orientations
por: Vrtis, Kyle B., et al.
Publicado: (2013)

Molecular basis for DNA strand displacement by NHEJ repair polymerases
por: Bartlett, Edward J., et al.
Publicado: (2016)

5-methylcytosine-sensitive variants of Thermococcus kodakaraensis DNA polymerase
por: Huber, Claudia, et al.
Publicado: (2016)

Limited reverse transcriptase activity of phi29 DNA polymerase
por: Krzywkowski, Tomasz, et al.
Publicado: (2018)

PCNA accelerates the nucleotide incorporation rate by DNA polymerase δ
por: Mondol, Tanumoy, et al.
Publicado: (2019)

Revealing the role of the product metal in DNA polymerase β catalysis
por: Perera, Lalith, et al.
Publicado: (2017)

Oxidative damage diminishes mitochondrial DNA polymerase replication fidelity
por: Anderson, Andrew P, et al.
Publicado: (2020)

DNA polymerase θ specializes in incorporating synthetic expanded-size (xDNA) nucleotides
por: Kent, Tatiana, et al.
Publicado: (2016)

Substrate conformational dynamics facilitate structure-specific recognition of gapped DNA by DNA polymerase
por: Craggs, Timothy D, et al.
Publicado: (2019)

Alteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamics
por: Xia, Shuangluo, et al.
Publicado: (2013)

Bacteriophage λ N protein inhibits transcription slippage by Escherichia coli RNA polymerase
por: Parks, Adam R., et al.
Publicado: (2014)

Loop II of DNA polymerase beta is important for polymerization activity and fidelity
por: Lin, George C., et al.
Publicado: (2007)

The high fidelity and unique error signature of human DNA polymerase ε
por: Korona, Dagmara A., et al.
Publicado: (2011)

Indirect read-out of the promoter DNA by RNA polymerase in the closed complex
por: Debnath, Subrata, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_qrrprq4q0vjou315it68ru0b7a