The PMC2NT domain of the catalytic exosome subunit Rrp6p provides the interface for binding with its cofactor Rrp47p, a nucleic acid-binding protein

The exosome complex is a key component of the cellular RNA surveillance machinery and is required for normal 3′ end processing of many stable RNAs. Exosome activity requires additional factors such as the Ski or TRAMP complexes to activate the complex or facilitate substrate binding. Rrp47p promotes...

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Detalles Bibliográficos
Autores principales: Stead, Jonathan A., Costello, Joe L., Livingstone, Michaela J., Mitchell, Phil
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018643/
https://www.ncbi.nlm.nih.gov/pubmed/17704127
http://dx.doi.org/10.1093/nar/gkm614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018643/
https://www.ncbi.nlm.nih.gov/pubmed/17704127
http://dx.doi.org/10.1093/nar/gkm614

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