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Avoiding false-positive signals with nuclease-vulnerable molecular beacons in single living cells

There have been a growing number of studies where molecular beacons (MBs) are used to image RNA expression in living cells; however, the ability to make accurate measurements can be hampered by the generation of false-positive signals resulting from non-specific interactions and/or nuclease degradat...

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Detalles Bibliográficos
Autores principales: Chen, Antony K., Behlke, Mark A., Tsourkas, Andrew
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018645/
https://www.ncbi.nlm.nih.gov/pubmed/17702767
http://dx.doi.org/10.1093/nar/gkm593