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Design of an improved set of oligonucleotide primers for genotyping MeCP2(tm1.1Bird )KO mice by PCR
BACKGROUND: The strain of MeCP2(tm1.1Bird )mice is a broadly used model for Rett syndrome. Because males carrying the invalidated MeCP2 locus are sterile, this strain has to be maintained in a heterozygous state. All animals therefore have to be genotyped at every generation to discriminate those ca...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018688/ https://www.ncbi.nlm.nih.gov/pubmed/17764542 http://dx.doi.org/10.1186/1750-1326-2-16 |