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Targeting APOBEC3A to the viral nucleoprotein complex confers antiviral activity

BACKGROUND: APOBEC3 (A3) proteins constitute a family of cytidine deaminases that provide intracellular resistance to retrovirus replication and to transposition of endogenous retroelements. A3A has significant homology to the C-terminus of A3G but has only a single cytidine deaminase active site (C...

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Detalles Bibliográficos
Autores principales: Goila-Gaur, Ritu, Khan, Mohammad A, Miyagi, Eri, Kao, Sandra, Strebel, Klaus
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018723/
https://www.ncbi.nlm.nih.gov/pubmed/17727729
http://dx.doi.org/10.1186/1742-4690-4-61