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Cell Cycle Genes Are the Evolutionarily Conserved Targets of the E2F4 Transcription Factor

Maintaining quiescent cells in G0 phase is achieved in part through the multiprotein subunit complex known as DREAM, and in human cell lines the transcription factor E2F4 directs this complex to its cell cycle targets. We found that E2F4 binds a highly overlapping set of human genes among three dive...

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Detalles Bibliográficos
Autores principales: Conboy, Caitlin M., Spyrou, Christiana, Thorne, Natalie P., Wade, Elizabeth J., Barbosa-Morais, Nuno L., Wilson, Michael D., Bhattacharjee, Arindam, Young, Richard A., Tavaré, Simon, Lees, Jacqueline A., Odom, Duncan T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2020443/
https://www.ncbi.nlm.nih.gov/pubmed/17957245
http://dx.doi.org/10.1371/journal.pone.0001061