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A strategy for detection of known and unknown SNP using a minimum number of oligonucleotides applicable in the clinical settings
Detection of unknown single nucleotide polymorphism (SNP) relies on large scale sequencing expeditions of genomic fragments or complex high-throughput chip technology. We describe a simplified strategy for fluorimetric detection of known and unknown SNP by proportional hybridization to oligonucleoti...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC202360/ https://www.ncbi.nlm.nih.gov/pubmed/14527341 http://dx.doi.org/10.1186/1479-5876-1-4 |