Metronidazole (Flagyl): characterization as a cytotoxic drug specific for hypoxic tumour cells.

The cytocidal properties of metronidazole against hypoxic mammalian cells are described. This chemotherapeutic action has been shown to be dependent on drug concentration and duration of exposure. The x-ray TCD50 for a murine anaplastic carcinoma was reduced from 6081 rad to 4643 rad when animals we...

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Detalles Bibliográficos
Autores principales: Foster, J. L., Conroy, P. J., Searle, A. J., Willson, R. L.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1976
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024956/
https://www.ncbi.nlm.nih.gov/pubmed/1276030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024956/
https://www.ncbi.nlm.nih.gov/pubmed/1276030

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