Dephenylation of N-phenyl-2-naphthylamine in dogs and its possible oncogenic implications.

N-Dephenylation of N-phenyl-2-naphthylamine (PBNA) is strictly limited in dogs, and a 5 mg/kg dose gives 0-10 microng of urinary 2-naphthylamine (BNA), which does not appear to undergo further metabolism. Neither 2-naphthylhydroxylamine (BNHA) nor 2-amino-1-naphthylsulphate were detected in the urin...

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Detalles Bibliográficos
Autores principales: Batten, P. L., Hathway, D. E.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1977
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025285/
https://www.ncbi.nlm.nih.gov/pubmed/856239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025285/
https://www.ncbi.nlm.nih.gov/pubmed/856239

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