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Dephenylation of N-phenyl-2-naphthylamine in dogs and its possible oncogenic implications.
N-Dephenylation of N-phenyl-2-naphthylamine (PBNA) is strictly limited in dogs, and a 5 mg/kg dose gives 0-10 microng of urinary 2-naphthylamine (BNA), which does not appear to undergo further metabolism. Neither 2-naphthylhydroxylamine (BNHA) nor 2-amino-1-naphthylsulphate were detected in the urin...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1977
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025285/ https://www.ncbi.nlm.nih.gov/pubmed/856239 |