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Development and application of a radioimmunoassay for methotrexate.

An antiserum to methotrexate has been produced in a sheep against a conjugate of ovalbumin and methotrexate (MTX) prepared using a water-soluble carbodiimide. The antibodies produced were specific for substances containing the 2,4-diamino pteridine structure. Naturally occurring folates did not inte...

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Detalles Bibliográficos
Autores principales: Aherne, G. W., Piall, E. M., Marks, V.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1977
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025394/
https://www.ncbi.nlm.nih.gov/pubmed/588422