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P-aminosalicylate metabolism in cancer patients sensitive and resistant to chemotherapy.

A reduced response of a tumour to chemotherapy may be due to the host's drug metabolism. To test this hypothesis, we measured the metabolism of a model drug, para-aminosalicylate (PAS). Volunteers and cancer patients ingested a single oral dose (2 g) of PAS and we measured the plasma disappeara...

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Detalles Bibliográficos
Autores principales: Lavigne, J. G., Barry, A., d'Auteuil, C., Delage, J. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1977
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025501/
https://www.ncbi.nlm.nih.gov/pubmed/577182