Hsp90 Inhibition Decreases Mitochondrial Protein Turnover

BACKGROUND: Cells treated with hsp90 inhibitors exhibit pleiotropic changes, including an expansion of the mitochondrial compartment, accompanied by mitochondrial fragmentation and condensed mitochondrial morphology, with ultimate compromise of mitochondrial integrity and apoptosis. FINDINGS: We ide...

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Detalles Bibliográficos
Autores principales: Margineantu, Daciana H., Emerson, Christine B., Diaz, Dolores, Hockenbery, David M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2031825/
https://www.ncbi.nlm.nih.gov/pubmed/17957250
http://dx.doi.org/10.1371/journal.pone.0001066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2031825/
https://www.ncbi.nlm.nih.gov/pubmed/17957250
http://dx.doi.org/10.1371/journal.pone.0001066

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