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Deletion analysis of chromosome 8p in sporadic colorectal adenomas.

In order to assess the stage of colorectal tumorigenesis at which chromosome 8p loss of heterozygosity (LOH) occurs, 56 sporadic adenomas were examined for LOH at four polymorphic loci which show frequent LOH in carcinomas. LOH was found in only 5 out of 51 (9.8%) informative adenomas, whereas studi...

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Detalles Bibliográficos
Autores principales: Cunningham, C., Dunlop, M. G., Bird, C. C., Wyllie, A. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033333/
https://www.ncbi.nlm.nih.gov/pubmed/8018534