Evaluation of novel ammine/amine platinum (IV) dicarboxylates in L1210 murine leukaemia cells sensitive and resistant to cisplatin, tetraplatin or carboplatin.

Seventeen alkylamine ammine dicarboxylatodichloroplatinum(IV) complexes of general structure c,t,c-[PtCl2(OCOR1)2NH3(RNH2)], where R = aliphatic or alicyclic and R1 = aliphatic or aromatic, have been evaluated against L1210 cell lines with acquired resistance to cisplatin (10-fold), tetraplatin (34-...

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Detalles Bibliográficos
Autores principales: Orr, R. M., O'Neill, C. F., Nicolson, M. C., Barnard, C. F., Murrer, B. A., Giandomenico, C. M., Vollano, J. F., Harrap, K. R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1994
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033379/
https://www.ncbi.nlm.nih.gov/pubmed/8080724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033379/
https://www.ncbi.nlm.nih.gov/pubmed/8080724

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