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Establishment of a murine leukaemia cell line resistant to the growth-inhibitory effect of bryostatin 1.

Bryostatin 1 is a novel macrocyclic lactone activator of protein kinase C (PKC) which has clinical potential as an anti-cancer agent. The mechanism of action of this agent is unknown, but protein kinase C has been implicated. In order to investigate this possibility, we have developed P388 sublines...

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Detalles Bibliográficos
Autores principales: Prendiville, J., McGown, A. T., Gescher, A., Dickson, A. J., Courage, C., Pettit, G. R., Crowther, D., Fox, B. W.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033429/
https://www.ncbi.nlm.nih.gov/pubmed/7917900