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Modulation of cisplatin cytotoxicity by sulphasalazine.

The efficacy of cisplatin [cis-diamminedichloroplatinum (II); DDP] is hampered by acquired or de novo resistance of malignant cells to its cytotoxic effects. We have previously reported that cisplatin resistance parallels glutathione S-transferase (GST) activity in several human small-cell lung canc...

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Detalles Bibliográficos
Autores principales: Awasthi, S., Sharma, R., Singhal, S. S., Herzog, N. K., Chaubey, M., Awasthi, Y. C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033482/
https://www.ncbi.nlm.nih.gov/pubmed/7914420