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Diagnosis of pancreatic adenocarcinoma by polymerase chain reaction from pancreatic secretions.

As mutations at codon 12 of the Ki-ras oncogene have been shown to occur in 90% of pancreatic adenocarcinomas, a novel strategy for the detection of these mutations in pancreatic secretions obtained at routine endoscopies was developed. Ki-ras DNA was amplified and screened for the presence of mutat...

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Detalles Bibliográficos
Autores principales: Trümper, L. H., Bürger, B., von Bonin, F., Hintze, A., von Blohn, G., Pfreundschuh, M., Daus, H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033495/
https://www.ncbi.nlm.nih.gov/pubmed/8054276