Frequency of allele loss of DCC, p53, RBI, WT1, NF1, NM23 and APC/MCC in colorectal cancer assayed by fluorescent multiplex polymerase chain reaction.

We report here the use of multiplex fluorescent polymerase chain reaction (PCR) for quantitative allele loss detection using microsatellites with 2-5 base pair repeat motifs. Allele loss of APC, DCC, p53 and RB1 in colorectal tumours has been reported previously using a variety of methods. However,...

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Detalles Bibliográficos
Autores principales: Cawkwell, L., Lewis, F. A., Quirke, P.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1994
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033544/
https://www.ncbi.nlm.nih.gov/pubmed/7947085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033544/
https://www.ncbi.nlm.nih.gov/pubmed/7947085

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