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Interaction of tamoxifen with the multidrug resistance P-glycoprotein.

Tamoxifen is an anti-oestrogen which is currently being assessed as a prophylactic for women at high risk of breast cancer. Taxoxifen has also been shown to reverse multidrug resistance in P-glycoprotein (P-gp)-expressing cells, although the mechanism of action is unknown. In this study we demonstra...

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Detalles Bibliográficos
Autores principales: Callaghan, R., Higgins, C. F.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033580/
https://www.ncbi.nlm.nih.gov/pubmed/7841043