Detection of hypoxia by measurement of DNA damage in individual cells from spheroids and murine tumours exposed to bioreductive drugs. I. Tirapazamine.

The possibility of using tirapazamine (SR 4233) to identify hypoxic cells in multicell spheroids and murine tumours was examined by measuring tirapazamine-induced DNA damage to individual cells from multicell spheroids and SCCVII murine tumours. Fluorescence microscopy and image analysis were used t...

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Detalles Bibliográficos
Autor principal: Olive, P. L.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033654/
https://www.ncbi.nlm.nih.gov/pubmed/7880735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033654/
https://www.ncbi.nlm.nih.gov/pubmed/7880735

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