Inhibition of N-linked glycosylation of P-glycoprotein by tunicamycin results in a reduced multidrug resistance phenotype.

Characterisation of altered glycosylation of P-glycoprotein (P-gp) found associated with the absence of a multidrug resistance (MDR) phenotype in cell lines prompted an investigation to assess the role of post-translational processing in establishing P-gp efflux pump functionally. The clone A cell l...

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Detalles Bibliográficos
Autores principales: Kramer, R., Weber, T. K., Arceci, R., Ramchurren, N., Kastrinakis, W. V., Steele, G., Summerhayes, I. C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033717/
https://www.ncbi.nlm.nih.gov/pubmed/7710927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033717/
https://www.ncbi.nlm.nih.gov/pubmed/7710927

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