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Targeting gene transcription: a new strategy to down-regulate c-erbB-2 expression in mammary carcinoma.

Overexpression of the c-erbB-2 proto-oncogene in mammary carcinoma is frequently associated with amplification of the c-erbB-2 gene, but it also occurs from single-copy gene. Studies in mammary-derived cell lines have shown that, whether or not the gene is amplified, there is a 6- to 8-fold increase...

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Detalles Bibliográficos
Autores principales: Hollywood, D. P., Hurst, H. C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033738/
https://www.ncbi.nlm.nih.gov/pubmed/7710940