Delivery of the ribosome-inactivating protein, gelonin, to lymphoma cells via CD22 and CD38 using bispecific antibodies.

It is well established that bispecific antibodies (BsAbs) can be used effectively in targeting the ribosome-inactivating protein (RIP), saporin, against neoplastic B cells. We have now extended this delivery system for use with gelonin. By measuring antigen-binding characteristics and epitope mappin...

Descripción completa

Detalles Bibliográficos
Autores principales: French, R. R., Penney, C. A., Browning, A. C., Stirpe, F., George, A. J., Glennie, M. J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033802/
https://www.ncbi.nlm.nih.gov/pubmed/7734325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033802/
https://www.ncbi.nlm.nih.gov/pubmed/7734325

Ejemplares similares