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Prolonged survival of mice with human gastric cancer treated with an anti-c-ErbB-2 monoclonal antibody.

A monoclonal antibody (MAb), 4D5, specifically recognising an extracellular epitope of the c-ErbB-2 protein, inhibited the growth of human gastric cancer overexpressing c-ErbB-2 severe combined immunodeficient (SCID) mice. This antibody also reduced the mass of established tumours xenografted into S...

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Detalles Bibliográficos
Autores principales: Ohnishi, Y., Nakamura, H., Yoshimura, M., Tokuda, Y., Iwasawa, M., Ueyama, Y., Tamaoki, N., Shimamura, K.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033805/
https://www.ncbi.nlm.nih.gov/pubmed/7734322