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Prolonged survival of mice with human gastric cancer treated with an anti-c-ErbB-2 monoclonal antibody.
A monoclonal antibody (MAb), 4D5, specifically recognising an extracellular epitope of the c-ErbB-2 protein, inhibited the growth of human gastric cancer overexpressing c-ErbB-2 severe combined immunodeficient (SCID) mice. This antibody also reduced the mass of established tumours xenografted into S...
Autores principales: | Ohnishi, Y., Nakamura, H., Yoshimura, M., Tokuda, Y., Iwasawa, M., Ueyama, Y., Tamaoki, N., Shimamura, K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1995
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033805/ https://www.ncbi.nlm.nih.gov/pubmed/7734322 |
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