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Induction of apoptosis by anti-cancer drugs with disparate modes of action: kinetics of cell death and changes in c-myc expression.

Incubation of CCRF CEM C7A human lymphoblastic leukaemia cells with etoposide (VP16) or N-methylformamide (NMF) induced apoptotic cell death. The kinetics of onset of apoptosis was determined and compared with that for dexamethasone-treated cells. The drugs induced 50% apoptosis at different rates:...

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Detalles Bibliográficos
Autores principales: Wood, A. C., Elvin, P., Hickman, J. A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033809/
https://www.ncbi.nlm.nih.gov/pubmed/7734316