EO9: relationship between DT-diaphorase levels and response in vitro and in vivo.

EO9 [3-hydroxy-5-aziridinyl-1-methyl-2(1H-indole-4,7-dione)-prop-beta-en- alpha-ol] was selected for clinical trial in Europe because of its preclinical profile but also because of its distinct mechanism of bioactivation. Several studies have shown that cells rich in DT-diaphorase may be particularl...

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Detalles Bibliográficos
Autores principales: Collard, J., Matthew, A. M., Double, J. A., Bibby, M. C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033862/
https://www.ncbi.nlm.nih.gov/pubmed/7779711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033862/
https://www.ncbi.nlm.nih.gov/pubmed/7779711

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