An etoposide-resistant lung cancer subline overexpresses the multidrug resistance-associated protein.

We have characterised an etoposide-resistant subline of the small-cell lung cancer cell line, UMCC-1, derived at our centre. Subline UMCC-1/VP was developed by culturing the parent line in increasing concentrations of etoposide over 16 months. UMCC-1/VP is 20-fold resistant to etoposide by MTT assay...

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Detalles Bibliográficos
Autores principales: Doyle, L. A., Ross, D. D., Ordonez, J. V., Yang, W., Gao, Y., Tong, Y., Belani, C. P., Gutheil, J. C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033885/
https://www.ncbi.nlm.nih.gov/pubmed/7669558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033885/
https://www.ncbi.nlm.nih.gov/pubmed/7669558

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