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Presence of a heterozygous substitution and its relationship to DT-diaphorase activity.

A point mutation in the mRNA of NADP(H): quinone oxidoreductase 1 (NQO1, DT-diaphorase) is believed to be responsible for reduced enzyme activity in the adenocarcinoma BE cell line. The present study examined nine cultured human non-cancerous fibroblast cell strains, five of which were from members...

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Detalles Bibliográficos
Autores principales: Kuehl, B. L., Paterson, J. W., Peacock, J. W., Paterson, M. C., Rauth, A. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033894/
https://www.ncbi.nlm.nih.gov/pubmed/7669561