Multiple polymorphisms, but no mutations, in the WAF1/CIP1 gene in human brain tumours.

The cyclin kinase inhibitor WAF1/CIP1, also termed CDKN1, mediates p53-induced cell cycle arrest in response to DNA damage. This property makes it an attractive tumour-suppressor candidate for a p53-associated tumour-suppressor gene. In order to investigate the role of WAF1/CIP1 in the pathogenesis...

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Detalles Bibliográficos
Autores principales: Koopmann, J., Maintz, D., Schild, S., Schramm, J., Louis, D. N., Wiestler, O. D., von Deimling, A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033923/
https://www.ncbi.nlm.nih.gov/pubmed/7577473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033923/
https://www.ncbi.nlm.nih.gov/pubmed/7577473

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