Chemosensitisation of spontaneous multidrug resistance by a 1,4-dihydropyridine analogue and verapamil in human glioma cell lines overexpressing MRP or MDR1.

Multidrug resistance phenotypes in human tumours are associated with the overexpression of the 170 kDa P-glycoprotein encoded by the multidrug resistance 1 (MDR1) gene, and also with that of the non-P-glycoprotein-mediated multidrug resistance gene, MRP, which encodes a 190 kDa membrane ATP-binding...

Descripción completa

Detalles Bibliográficos
Autores principales: Abe, T., Koike, K., Ohga, T., Kubo, T., Wada, M., Kohno, K., Mori, T., Hidaka, K., Kuwano, M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033970/
https://www.ncbi.nlm.nih.gov/pubmed/7640227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033970/
https://www.ncbi.nlm.nih.gov/pubmed/7640227

Ejemplares similares